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抗氧化营养素对啮齿动物脑缺血-再灌注损伤的保护作用 被引量：4

The investigation of apoptosis on the mechanism of cerebral vasospasm after subarachnoid hemorrhage
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摘要 啮齿动物大脑缺血-再灌注会导致迟发性神经元死亡(DND)。其中蒙古沙鼠和具有脑卒中倾向的原发性高血压大鼠(SHRSP)常常被用作实验性卒中的模型。作者主要介绍了维生素E、绿茶提取物、银杏叶提取物、白藜芦醇、烟酸、异黄酮素等抗氧化营养素对啮齿动物脑缺血-再灌注损伤的良好保护作用。 Cerebral ischemia and reperfusion can cause delayed neuronal death in rodents, such as Mongolian gerbils and stroke-prone spontaneously hypertensive rats （SHRSP）, which are used as an experimental stroke model. The protective effects of antioxidant nutrients such as vitamin E, green tea extract, ginkgo biloba extract, resveratrol, niacin and isoflavones in cerebral ischemia and reperfusion brain injury were reviewed.
作者 茅磊 史继新
机构地区 南京大学医学院临床学院(南京军区南京总医院)神经外科
出处 《医学研究生学报》 CAS 2007年第1期101-103,共3页 Journal of Medical Postgraduates
基金 南京军区南京总医院科研基金资助项目(批准号:2005074)
关键词 缺血-再灌注损伤 迟发性神经元死亡 抗氧化营养素 啮齿动物 Ischemia and reperfusion injury Delayed neuronal death Antioxidant nutrients Rodents
分类号 R743.3 [医药卫生—神经病学与精神病学]
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参考文献13

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二级参考文献14

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共引文献2

同被引文献52

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医学研究生学报
2007年 第1期

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