摘要
２４例门脉高压、脾肿大伴脾亢患者分脾次全切除和全脾切除组，对其手术前后的Ｔ淋巴细胞转化率、ＩｇＡ、ＩｇＧ、ＩｇＭ进行了对比观察，并观察了保脾组手术前后的Ｔ细胞亚群变化情况，发现脾次全切除，保留原脾组织６ｃｍ×５ｃｍ×４ｃｍ大小，能较好地维持各项免疫指标在正常范围。而全脾切除术后Ｔ淋巴细胞转化率，ｌｇＡ、ｌｇＭ呈持续下降，直至术后３个月仍处于最低值。认为脾次全切除，保留适当的残脾能较好地维持其免疫功能。
In order to investigate the changes in T-cell subsets, the transfomed rate of T-cell, the level of IgG, IgM and IgA after operation, twenty-four patients were divided into subtotal splenectomy group(SSG) and total splenectomy group (TSG).It was found that in SSG the conserved residual tissue of spleen(6cm × 5cm × 4cm)can keep the detected immunolgical indexes in normal range well, but in TSG the levels of IgM,IgA and the transformed rate of T-cell descended continually and did not recover the previous level up to three months after operation. Suggesting that the conserved residual tissue of spleen can keep its immunological function well.
出处
《河北医学》
CAS
1996年第6期551-553,共3页
Hebei Medicine
关键词
脾肿大
脾次全切除
免疫功能
Splenomegaly
Subtotal Splenectomy
Immunological function
