摘要
目的建立一种灵敏度高、准确可靠、实用的趾甲含砷量的分析方法，为地方性砷中毒防治提供实验室检测依据。方法样品用2％的中性洗涤剂，温水浸泡30min清水洗净，用硝酸-高氯酸（2：1）3ml消化0．2g趾甲样。应用氢化物发生——原子荧光法（HG—AFS）测定趾甲砷。结果本方法的线性范围为0-100μg／L，相关系数≥0．9995，取样量为0．2g时，检出限为0．0243μg／g；该方法精密度较高，相对标准偏差（RSD）〈10％；加标回收率在90％以上。结论该方法灵敏、准确可靠，操作较简单、快速，适用于地方性砷中毒病区趾甲砷的测定分析。
Objective To establish a new sensitive and reliable method for determination of total arsenic in nail. Methods The nail samples were washed with 2% liquid detergent and digested with 3 ml of nitric acidperchloric acid system （2 ： 1 ）. The arsenic in nail was determined with hydride generator-atomic fluorescence spectrometry. Results The linear range of the method was 0 - 100 μg/L. The correlation coefficient was larger than 0.999. The detectable limit was 0.0243μg/g when 0.2 g of sample was taken. This method had a higher degree of precision, with a RSD lower than 10% and a recovery rate higher than 90%. Conclusions This is an easy and fast method with sensitivity and accuracy for detecting endemic arsenism.
出处
《中国地方病学杂志》
CAS
CSCD
北大核心
2007年第1期93-94,共2页
Chinese Jouranl of Endemiology
基金
中国疾病预防控制中心资助项目（2004）
