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雪莲注射液长期毒性实验研究 被引量:7

Experimental study on chronic toxicity of Xuelian injection
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摘要 目的了解雪莲注射液是否具有长期毒性作用,为临床应用提供参考依据。方法通过腹腔注射给大鼠不同剂量的雪莲注射液,连续给药90 d,并持续观察14 d。结果连续注射给药90 d后,大鼠未出现外观、血常规、肝肾功能等血生化及13种脏器组织的毒性变化。结论该药无明显毒副作用,具有临床用药的安全性。 Objective It is to test whether Xuelian injection had long term toxicity so as to provide information for clinical application. Methods The rats were given Xuelian injection by intraperitoneal injection for 90 days and were observed for 14 days continuous.ly in order to test the drug's toxicity. Resnlts After stopping medicine, no abnormal changes of appearance, blood biochemical reaction routine such as routine blood test,function of liver and kidney, and pathological examination of 13 kinds of visceras' tissue. Conclusion Xuelian injection has no evident toxic and side effect, so it is safe to use in clinic.
出处 《现代中西医结合杂志》 CAS 2007年第4期458-460,共3页 Modern Journal of Integrated Traditional Chinese and Western Medicine
关键词 雪莲注射液 长期毒性实验 Xuelian injection chronic toxicant experiment
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参考文献2

  • 1徐淑云.药理实验方法学[M].2版.北京:人民卫生出版社,1994:1433-1439 被引量:2
  • 2国家药品监督管理局.中药新药研究的技术要求[Z].,1999.. 被引量:3

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