摘要
目的探讨血清CystatinC浓度在急性心肌梗死患者发病不同时期的变化。方法采用速率散射比浊法测定急性心肌梗死患者发病48h内及1周后、不稳定型心绞痛患者、对照组血清CystatinC水平。结果急性心肌梗死患者早期血清CystatinC水平(0.78±0.15)与不稳定型心绞痛(0.89±0.22)、对照组(0.84±0.21)相比明显降低(P=0.028),但急性心肌梗死发病1周后(1.28±0.20)接近正常,甚至有所增高(P=0.04)。血清CystatinC水平与年龄、肌酐呈正相关。结论血清CystatinC水平在急性心肌梗死早期明显下降。
Objective To explore the changes of serum Cystatin C and its value as a sign of early diagnosis and predicting stability of atherosclerotic plaque in patients with acute myocardial infarction. Methods In this study, seruma levels of Cystatin C have been investigated in patients with acute myocardial infarction, unstable angina and controls. Results Patients with acute myocardial infarction during onset showed significantly lower levels of Cystatin C compared to unstable angina and controls, but levels were nearly normal or high in a week after the acute event. Cystatin C levels were positively correlated with age and creatinine. Conclusion Cystatin C is decreased in acute myocardial infaretion during onset.
出处
《中国心血管病研究》
CAS
2007年第1期27-29,共3页
Chinese Journal of Cardiovascular Research
