摘要
通过柱层析和高效液相层析从白喉乌头（Ａｃｏｎｉｔｕｍ ｌｅｕｃｏｓｔｏｍ ｕｍ Ｗｏｒｏｓｃｈ．）的根中分离得到４种二萜生物碱，通过各种光谱数据的解析鉴定了它们的结构，其中一种是新化合物，命名为喉乌碱（ｌｅｕ－ｃｏｓｔｉｎｅ，Ⅱ）；其它为已知化合物ｌｅｕｃｏｎｉｎｅ （Ⅰ）、ｄｅｈｙｄｒｏａｃｏｓａｎｉｎｅ （Ⅲ）和ｓｅｐａｃｏｎｉｔｉｎｅ （Ⅳ）。
Four diterpenoid alkaloids were isolated by means of column chromatography and preparative HPLC from the roots of Aconitum leucostomum Worosch. Their structures were determined from the spectral data. One of them was found to be a new compound named leucostine (Ⅱ). The other three are known alkaloids, leuconine (Ⅰ), dehydroacosanine (Ⅲ) and sepaconitine(Ⅳ).
基金
国家自然科学基金
关键词
乌头属
白喉乌头
二萜生物碱
喉乌碱
Aconitum leucostomum
Diterpenoid alkaloids
leucostine
