摘要
目的探讨放射治疗脑转移瘤患者的年龄、原发肿瘤部位、转移灶数量、合并症等因素对生存时间的影响,指导个体化临床治疗。方法回顾分析和对比资料完整的107例住院放疗脑转移瘤患者的临床各相关因素及患者生存时间。结果>60岁组生存期短于≤60岁组(P<0.05);有颅外未控病灶患者生存期短于无颅外未控病灶者(P<0.01);合并糖尿病、脑血管病患者生存期短于无合并症者(P<0.05);不同原发肿瘤各组间生存时间差异有显著性(P<0.01);转移瘤数量13个者较3个者以上生存期延长(P<0.01);不同性别患者生存期差异无显著性(P>0.05)。结论老年,颅外病灶未控,合并糖尿病、脑血管病及转移瘤>3个是脑转移瘤患者的预后不良因素。
Objective To explore the factors influencing survival time of patients with brain metastatic tumor after radiotherapy, such as age, original site of tumor, the number of metastic tumors and complications,and to guide clinical individualized treatment. Methods The clinical data of 107 hospitalized patients with brain metastatic tumors after radiotherapy were reviewed and analyzed for the relative factors and survival time. Results For the survival time the group aged 〉 60 years was shorter than the group ≤ 60 years （P 〈 0.05 ）, the group with extracranial uncontrolled focus was shorter than the group without extracranial uncontrolled focus（P 〈 0. 01 ）, the group with complication of diabetes or brain vascular disease was shorter than the group without complication （P 〈 0.05 ）, there was statistically significant differences between groups of different primary tumors（P 〈0.01）. The group with number of tumors 〉3 had a shorter survival time compared with the group having number of tumors ≤3 （ P 〈0.01 ）. There was no statistically significant difference between different sex groups （ P 〉 0. 05 ）. Conclusions Agedness, extracranial uncontrolled focus, complication of diabetes or brain vascular disease and the number of tumors 〉 3 were infaust factors to survival.
出处
《中国肿瘤临床与康复》
2006年第6期509-511,共3页
Chinese Journal of Clinical Oncology and Rehabilitation
