摘要
目的探讨了前列腺癌患者血清IGF-Ⅰ和SIL-2R水平及意义。方法应用放射免疫分析和酶联免疫法对31例前列腺癌患者进行了血清IGF-Ⅰ和SIL-2R检测,并与30名正常人作比较。结果前列腺癌患者血清IGF-Ⅰ和SIL-2R水平非常显著地高于正常人组(P<0.01),两者呈明显正相关(r=0.6182,P<0.01)。结论检测前列腺癌患者血清IGF-Ⅰ和SIL-2R水平对诊断、治疗和预后观察具有重要的临床价值。
Objective To investigate the significance of changes of serum IGF -Ⅰ and SIL - 2R levels in patients with prostatic cancer. Methods Serum IGF- Ⅰ levels （with RIA） and SIL-2R levels （with ELISA） were measured in 31 patients with prostatic cancer and 30 controls. Results Serum levels of IGF - Ⅰ and SIL - 2R in the 31 patients were significantly higher than those in controis （P 〈0.01 ）, serum IGF - Ⅰ and SIL -2R levels were mutually positively correlated （r =0. 6182, P 〈0.01 ）. Conclusion Serum IGF- Ⅰ and SIL-2R were uselul markers for prostatic cancer.
出处
《放射免疫学杂志》
CAS
2006年第6期469-470,共2页
Journal of Radioimmanology
关键词
前列腺癌
胰岛素样生长因子-Ⅰ
可溶性白细胞介素-2受体
prostatic cancer, insulin -like growth factor- Ⅰ （IGF- Ⅰ ）, soluble interleukin -2 receptor （SIL- 2R）
