摘要
目的：探讨女性乳腺癌的危险因素,为有效的预防控制措施的建立提供依据.方法：应用成组病例对照的研究方法,收集经组织病理学确诊为乳腺癌的女性病例121名及社区来源的健康女性对照211名.采用统一的问卷调查表获取病例和对照乳腺癌相关危险因素的信息.采用非条件logistic回归进行单因素和多因素分析.结果：多因素分析：与乳腺癌发病有关的变量为吸烟、未足月产次数多及家禽肉类摄入量多,OR值及95%CI分别为15.093（1.014～224.622）、1.759（1.006～3.073）和1.811（1.024～3.203）;对乳腺癌有保护作用的变量是奶制品及豆制品摄入量多,OR值及95%CI分别为0.763（0.624～0.933）和0.626（0.422～1.044）.经分组分析,绝经组奶制品摄入量多具有保护作用;非绝经组奶制品及豆制品摄入量多具有保护作用,而吸烟增加患乳腺癌的危险.结论：吸烟、未足月产次数多、家禽肉类摄入量多是乳腺癌的危险因素,奶制品及豆制品摄入量多是乳腺癌的保护因素.
Objective： To study the major risk factors of female breast cancer in Sichuan, a case oontrol study was designed. Methods： 121 breast cancer patients with histopathological diagnosis and 211 healthy oommunity controls were included. All data were collected with a unified questionnaire. Unconditional logistic regression model was used to analyzed the significant risk factors. Results： Active smoking, abortion, taking poultry, milk and .soybean food frequently were related to breast cancer, the ORs were 15.093 （1.014-224.622）, 1.759 （1.006-3.073）, 1.811 （1.024-3.203）, 0.763 （0.624-0.933） and0.626 （0.422- 1.044）, respectively. Subgroup analyses showed that taking milk frequently Call decrease risk of breast cancer in postmenopausal women, while risk in pre- menopausal women were associated with milk intake, soybean food intake ,and smoking. Conclusion： Taking poultry frequently, abortion and active smoking are risk factors for breast cancer, while taking milk and soybean food frequently have beneficial effects of protecting individual from breast cancer.
出处
《现代预防医学》
CAS
北大核心
2006年第12期2233-2235,共3页
Modern Preventive Medicine
基金
四川大学青年科学研究基金(0040405505010)
四川省科技厅项目04JY029-025-2
关键词
乳腺癌
危险因素
病例对照
Breast cancer
Risk factor
Case-control study
