摘要
目的：研究不同宫内节育器（ＩＵＤ）对子宫内膜螺旋动脉形态的影响，为防治出血副反应提供理论依据。方法：取未放置ＩＵＤ、放置ＴＣｕ２２０ＣＩＵＤ及放置γ消炎痛ＣｕＩＵＤ３个月后妇女各３例的分泌晚期子宫内膜，应用电子计算机三维重建技术，重建子宫内膜螺旋动脉。结果：未放置ＩＵＤ的子宫内膜，螺旋动脉的螺旋状盘曲较均匀，平均管径２２．６９μｍ，曲率０．９６，桡率１．２７；放置ＴＣｕ２２０ＣＩＵＤ后，螺旋动脉盘曲不均匀，呈团状网状迂曲，平均管径１７．９９μｍ，曲率１．４８，桡率１．８６；放置γ消炎痛ＣｕＩＵＤ后，螺旋动脉变化与放置前相似。结论：含铜ＩＵＤ影响子宫内膜螺旋动脉的发育成熟，而消炎痛能对抗之。利用计算机三维重建技术，可重建人子宫内膜螺旋动脉。
Objective:Toinvestigatethemicro-threedimensionalchangesofendometrialspiralarteriesafterinsertionofdiferentintrauterinedevices(IUD).Methods:Nineendometriumspeci-menswereobtainedfromfertileagewomen:3frompreinsertion,3obtained3monthsafterinsertionofTCu220CIUD,and3specimensobtained3monthsafterinsertionofγCuIUD(releasingin-domethacin20μg/day).Alsampleswerecolectedinlatesecretoryphaseandweresectionedserial-ly.ByaTVcamera,theimagesofsectionsweresentfromalightmicroscopetoacomputerandcon-vertedintodigitaldata.Thespiralarteriesofendometriumwerereconstructedandvisualizedonaworkstationbymeansofthesoftwarepackageforthethreedimensionalreconstructionandvisualiza-tion.Thecurvatureandtorsionofthespiralarterieswerecalculated.Results:Inpreinsertiongroup,thespiralarteriescurvedregularlyinthreedimensions,andtheaveragediameterwas22.69μm,theaveragecurvaturewas0.96andtheaveragetorsionwas1.27.ThespiralarteriesofγCuIUDgrouphadsimilarappearancesasthepreinsertiongroup.However,inTCu220CIUDgroup,thecurveswereirregular,andtheaveragediameterwas17.99μm,theaveragecurvaturewas1.48andaveragetorsion1.86.Conclusion:Thethreedimensionalreconstructionofhumanendometrialspiralarterieswasdonebymeansofcomputerassistedreconstructiontechnologyforthefirsttime.Theendometri-umspiralarterieschangedinmorphologyafterinsertionofcopperIUD,andindomethacinmayhavecontraryefectsoncopper.
出处
《中华妇产科杂志》
CAS
CSCD
北大核心
1996年第9期523-525,共3页
Chinese Journal of Obstetrics and Gynecology
基金
国家八五攻关项目资助
关键词
子宫内膜
宫内避孕器
子宫出血
EndometriumIntrauterinedevicesUterinehemorrhage
