摘要
目的:探讨浸润性树突状细胞(TIDC)在胃癌组织中的表达及其意义。方法:采用免疫组化S-P法检测50例胃癌组织中DC细胞的表达。结果:TIDC高度浸润组的淋巴结转移率为21.4%,明显低于TIDC低度浸润组的78.6%,(P<0.05);而TIDC浸润程度与组织分化、浸润深度、肿瘤大小和性别无明显相关性(r分别为0.1072、0.1185、0.0916、0.0215,P均>0.05)。结论:TIDC可能具有抗肿瘤转移的作用。
Objective： To study the clinical implication of intratumoral TIDC in gastric carcinoma. Methods：The number of TIDC in 50 specimens of gastric carcinoma was detected by immunohistochemica technique, and DC infihration was graded as ＂marked＂ and ＂slight＂. Results： The lymph node metastasis rate was 21.4% in patients with marked infiltration and 78.6% in those with slight infiltration, which was statistically different（P〈0. 05） ,but the degree of TIDC infiltration was not associated with differentiation of the tumor cells, the depth of infiltration,tumor size and gender. Conclusion：TIDC in gastric carcinoma might play a role in anti-tumor metastasis.
出处
《实用临床医学（江西）》
CAS
2006年第11期9-10,共2页
Practical Clinical Medicine
关键词
胃癌
肿瘤浸润性树突状细胞
淋巴结转移
gastric carcinoma
tumor-infiltrating DC cell
lymph node metastasis
