摘要
目的对比双房右室三腔起搏与右房室双腔起搏预防阵发性快速房性心律失常（PAT）的效果。方法将具备起搏器适应证，抗心律失常药物（AAA）防治PAT无效的40例非甲亢及风心病患者分为2组，分别植入双房右室三腔起搏器（三腔组）及右房室双腔起搏器（双腔组），术后3、6、12、24及36个月各随访一次，观察比较PAT发作情况及生活质量（SF．36）评分。结果三腔组的PNF发作次数及SF-36评分在术后3个月时改善不显著（P〉0.05），但6、12、24及36个月时改善明显（P〈0．05）；三腔组服用AAA减少或停用。结论与普通双腔起搏比较，双房右室三腔起搏具有明显的预防PAT作用，其作用在中、长期逐渐显现，并能减少抗心律失常药物（AAA）的使用。
Objective To investigate the effectiveness of Cardiac dual and tri-chamber pacemaker in prevention of paroxysmal atrial tachyarrythmias（PAT）. Metbods Forty patients with pacemaker indication, frequent PAT, no rheumatic heart disease or hyperthyroidism, and retractory to anti-arrhythmic agents were divided into two groups. A dual-chamber（right atrium and venttieulum） or a tri-chamber pacemaker （two atria and right ventrieulum） was implanted into two groups respecively the patients were followed up in 3, 6, 12, 24 and 36 months alter the operation. Following parameters were compared ： （1）average frequencies of PAT per week and atrial premature beats per 24 hours; （2）inquiring quality of life（SF-36）. Results In dual chamber group, the frequencies of PAT and atrial premature beats as well as the quality of life were not significantly changed all over the follow-up times （P〉0.05）.In tri-chamber group, above parameters were not changed in the first three months（P〉0.05）, but in 6, 12, 24 and 36 months, they were changed significantly in comparison with both before operation and dual chamber group（P〈0.05）. Conclusion Tri-chamber pacing could significantly decreases the frequency of PAT in comparison with dual chamber pacing during the middle and long term lbllow-up times.
出处
《中华临床医学杂志》
2006年第11期14-16,共3页
Chinese Journal of Clinical Practical Medicine
关键词
心脏起搏
快速房性心律失常
电-解剖重构
Cardiac pacing Paroxysmal atrial tachyarrhythmias Electric -anatomical remodeling
