摘要
目的探讨应用组织追踪法(TT)测定左室壁收缩期位移评价左侧乳腺癌放疗后早期左室收缩功能的价值。方法35例左侧乳腺癌术后患者按照放疗进程分为3组:A组,放疗前;B组,放疗时间为3周、累积剂量30Gy;C组,放疗时间为5周、累积剂量50Gy。比较3组患者心脏左侧壁、后间隔、前壁、下壁、前间隔、后壁的基底段及中间段12个位点的收缩期最大位移。结果C组前壁、前间隔各位点的收缩期位移低于A组且差异具有非常显著性意义(P<0.01);C组前壁、前间隔各位点的收缩期位移低于B组且差异具有显著性意义(P<0.05);B组前壁、前间隔各位点的收缩期位移略低于A组,但差异无显著性意义(P>0.05);左侧壁、后间隔、下壁、后壁各位点收缩期位移在3组之间比较,差异均无显著性意义(P>0.05)。结论组织追踪法可无创、敏感、客观地评价左侧乳腺癌放疗早期左室收缩功能。
Objective To evaluate the value of tissue tracking （TT） in detecting left breast cancer radiotherapy-induced decrease of left ventricle early systolic function by measuring the systolic displacement of left ventricle. Methods TT were performed in 35 patients underwent radiotherapy for left breast cancer. According to the process of radiotherapy, the patients were divided into three groups（35 patients in groups A, B, C respectively）, group A（before radiation treatment）, group B （radiation dosage of 30 Gy, 3 weeks） and group C（radiation dosage of 50 Gy, 5weeks）. Systolic displacement were compared among three groups. Results Systolic displacement of group C in anterior wall, anterior septal were significant lower than those in group A（P〈0.01） ; systolic displacement of group C in anterior wall, anterior septal were lower than those in group B（P〈0.05） ; systolic displacement of group B in anterior wall, anterior septal were slightly lower than those in group A without statistical difference（P〉0.05） ; systolic displacement in left lateral wall, posterior septal, inferior wall, posterior wall had no significant difference among three groups（P〉0.05）. Conclusion TT is a nonvasive, sensitive, objective method to assess left breast cancer radiotherapy-induced early systolic function of left ventricle.
出处
《中国医学影像技术》
CSCD
北大核心
2006年第10期1573-1575,共3页
Chinese Journal of Medical Imaging Technology
关键词
组织追踪法
乳腺肿瘤
放射治疗
收缩功能
心室
Tissue tracking
Breast neoplasms
Radiotherapy
Systolic function
Heart ventricles
