摘要
目的初步探讨黄芪注射液加纳洛酮治疗急性脑出血的临床疗效。方法分别采用黄芪注射液治疗方案(A组:51例)、纳洛酮治疗方案(B组:49例)、黄芪注射液加纳洛酮治疗方案(C组:53例),对153例急性脑出血患者进行治疗,并于入院后第7、14、28天分别进行血肿体积、水肿容积测量和临床神经功能缺损程度评分。结果入院后第7天三组血肿体积、水肿容积、临床神经功能缺损程度评分比较差异均无统计学意义(P>0.05);入院后第14天C组分别与A、B组比较,血肿体积、水肿容积均显著减小(P<0.05),但A与B比较差异无统计学意义(P>0.05),三组临床神经功能缺损程度评分比较差异无统计学意义(P>0.05);入院后第28天C组分别与A、B组比较,血肿体积、水肿容积、临床神经功能缺损程度评分均有显著减少(P<0.05)。结论黄芪注射液加纳洛酮治疗方案是一种治疗急性脑出血更有效、更安全的方法。
Objective Proceeds the first step study on clinical effect of intravenous infusion of huangqi and naloxone in treating acute cerebral hemorrhage. Methods 153 patients were randomly divided into 3 groups：2 control groups ： group A intravenous infusion of （ huangqi, 51 patients ）, group B （ naloxone, 49 patients）, and treatment group ： group C （intravenous infusion of huangqi and naloxone ,53 patients）. The end points included volume of hematoma,dimension of edema and clinical neurological deficits scales of stroke. Results Treatment group whose volume of hematoma was（ 18±10）ml,and dimension of edema was （12±11 ）ml was significantly reduced in comparison with the control groups（ A and B） in 14 days （ P 〈0.05 ） ,and in 28 days group C whose clinical neurological deficits scales of stroke was 12.02±10.64 was significantly reduced in comparison with the control groups（ A and B） （ P 〈0.05 ）. Adverse reaction wasnt increased in treatment group. Conclusion Treatment group was better than control groups in clinical efficacy and didnt increase adverse reaction events.
出处
《中原医刊》
2006年第22期8-9,共2页
Central Plains Medical Journal
关键词
脑出血
黄芪注射液
纳洛酮
Cerebral hemorrhage
Intravenous infusion of huangqi
Naloxone
