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可溶性血管内皮生长因子受体1与子痫前期研究进展 被引量:9

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摘要 可溶性血管内皮生长因子受体1(sFlt1)是血管内皮生长因子受体1的剪接变体,sFlt-1能阻断血管内皮生长因子和胎盘生长因子的生物学效应,因而造成全身内皮功能失调,产生高血压、蛋白尿等临床表现。子痫前期发病前5周循环中sFlt1水平就有显著升高,子痫前期患者体内高水平的sFlt1可作为预测指标。拮抗sFlt1药物在子痫前期及子痫治疗中的价值值得进一步探讨。
作者 李云 胡继芬
出处 《国外医学(妇产科学分册)》 CAS 2006年第5期346-349,共4页 Foreign Medical Sciences(Obstet Gynecol Fascicle)
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