摘要
本文报道了３２例经肝动脉插管栓塞化疗（ＴｒａｎｓｈｅｐａｔｌｉａｒｔｅｒｉａｌＣｈｅｍｏｔｈｅｒａｐｙａｎｄＥｍｂｏｌｉｚａｔｉｏｎ，ＴＡＣＥ）后二步手术的肝癌患者（二步手术组）的临床资料和手术后的随访情况。ＴＡＣＥ后肿瘤最大直径平均下降３．５６ｃｍ（３６．６％），４例降至５ｃｍ以下，ＡＦＰ平均下降７７．３％，５例转为正常，无一例出现严重并发症。二步手术组随访２年，１１例（３４．４％）复发，与同期３５例一步手术组（１４例４０．０％复发）比较、无明显差异。但二步手术组的平均复发时间为７．０９±３．２７个月，较一步手术组的４．２９±３．２９个月显著延长．以上结果表明，术前ＴＡＣＥ能杀死肿瘤细胞，缩小肿瘤体积，延长手术后无瘤生存时间，是治疗原发性肝癌的一种有效手段。
We analysised the effect of preoperation Transarterial Chemotherapy and Embolization(TACE) on the postoperation recurrence in 32 primary hepatic carcinoma (PHC) patients.After TACE, the mean maximum tumor diameter was reduced by 3. 56cm (36. 6%), and in 4 cases were reduced below 5cm;the value of AFP was reduced by 77.3%, and in 5 cases were converted into normal range.No severe complications were noticed. All patients were followed up for 2 years.11 patients(34.4%) were found with recurrence during that period. The recurrence rate was not significantly different with that of 35 PHC patients who just received resection and were followed up for 2 years. The interval time between operation and recurrent were 7.08±3. 27 months and 4.29 ±3. 29 months in two groups respectively without significantly difference between them. We concluded that preoperative TACE can kill tumor cells, shrink the tumor body and prolong the interval between operation and recurrence. So it is an effective management in the treatment of PHC.
出处
《临床外科杂志》
1996年第6期312-314,共3页
Journal of Clinical Surgery
关键词
肝癌
肝动脉插管栓塞
外科手术
Primary hepatic carcinoma
Transarterial chemotherapy and embolization
Resection
Recurrence
