摘要
目的总结非手术精子抽吸(NSA)联合ICSI对梗阻性无精子症患者的治疗意义,并探讨精子来源等对ICSI后胚胎结局的影响。方法回顾性分析642个ICSI周期,比较了睾丸抽吸精子和精液精子行ICSI后的受精率、优质胚胎率、临床妊娠率、种植率及胚胎停育率等。结果NSA睾丸精子组和精液精子组相比较,其2PN受精率、优质胚胎率、临床妊娠率、种植率及胚胎停育率之间均没有显著性差异(71．4％vs 73．2％, 73．1％vs 70．1％,34．2％vs 32．6％,22．3％vs 19．8％,21．3％vs 25．0％,P>0．05)。结论非手术抽吸睾丸精子联合ICSI是治疗梗阻性无精子症的一种有效方法。
Objectives To review non-surgical sperm aspiration in treatment of obstructive azoospermic patients and to evaluate the effect of source of sperm on ICSI cycles. Methods 237 ICSI cycles using testicular sperm from obstructive azoospermic men and 405 cycles using ejaculated sperm were retrospectively studied. Outcome of fertilization rate （FR）, clinical pregnancy rate （CPR）, implantation rate （IR）, advanced embryo rate and developmental atretic embryo rate after implantation were measured. Results Similar outcome on FR, advanced embryo rate, CPR, IR and developmental atretic embryo rate between the use of testicular and ejaculated sperm （71.4% vs 73.2%, 73.1% vs 70.1%, 34.2% vs 32.6%, 22.3% vs 19.8%, 21.3% vs 25%, P〉0.05 ） was obtained. Conclusion Non-surgically sperm aspiration is effective for azoospermic patients by ICSI.
出处
《中国男科学杂志》
CAS
CSCD
2006年第10期32-34,共3页
Chinese Journal of Andrology
