摘要
目的对梗阻性无精子症（OA）患者采用睾丸抽吸精子行胞浆内单精子注射（ICSI），观察活动精子是否提高受精率和妊娠率。方法回顾本院2007年至2010年就诊的268对夫妇行ICSI，男方行诊断性睾丸抽吸术确认均患有OA。其中237对夫妇进行胚胎移植，包括运动精子组182对和不动精子组55对夫妇。结果运动精子组和不动精子组的平均成熟卵泡数分别为14．16±7．46和14．08±9．40，平均正常受精卵子数分别为9．17±5．51和8．80±6．35，种植率分别为25．19％和28．69％，差异无统计学意义。两组的临床妊娠率差异也无统计学意义（运动精子组42．31％和不动精子组49．09％，P均〉0．05）。结论睾丸精子的活动率没有提高受精率和临床妊娠率，因此，睾丸内不动精子可以行ICSI。
Objective To explore the relationship between the motility of testicular spermatozoa and fertilization and pregnancy rate in patients undergoing in vitro intracytoplasmic sperm injection （ICSI）. Methods A total of 268 couples diagnosed as obstructive azoospermia who had undergone a sperm retrieval procedure in conjunction with IVF/ICSI cycles from 2007 to 2010, and in vitro fertilisation （IVF） were retrospectively evaluated. The 237 couples, divided into the motile group （182 couples） and the immotile group（55 couples）, underwent embryo transplantation. The impact of sperm motility on fertilization and clinical pregnancy rate was evaluated. Results There was no significant difference between the motile group and the immotile groups in the number of mature oocytes retrieved （14.16±7.46 vs 14.08±9.40）, the number of fertilized oocytes retrieved （9.17±5.51 vs 8.80±6.35） and implantation rate （25.19% vs 28.69%）. No significant difference in the clinical pregnancy rate was found between the motile group （42.31%） and immotile （49.09%） group. Conclusion No evidence was shown in sperm motility from the testicular samples ,which enhances fertilization or clinical pregnancy rate, so the nonmotile sperm from obstructive azoospermia can undergo ICSI.
出处
《中国男科学杂志》
CAS
CSCD
北大核心
2012年第2期38-40,共3页
Chinese Journal of Andrology
基金
基金项目：广东省省科技厅基金（2006836003016）,广东省卫生厅基金（A200609I）
关键词
无精子症
精子能动性
精子注射
细胞质内
azoospermia
sperm motility
sperm injections
intracytoplasmic
