摘要
本实验用25只成年杂种犬,随机结扎一侧股静脉,造成该侧膝部骨内高压模型。用综台指标进行观察,并在此模型上进行钻孔减压。结果表明:用此方法。可成功地造成该侧膝部骨内高压模型;切断组与不切断组差异无显著性,而不切断法更为简单可行;该方法造成骨内高压模型后,如果不给予减压处理,此高压可维持至少半年,也不能自行恢复到正常水平,钻孔减压术可使压力立即下降达48.7％,减压术后,压力保持于低压水平可达4个月:组织学改变与退行性骨关节炎的改变大体一致,从临床的角度考虑,人体类似的改变可能由于各种原因所致的长期静脉性淤血而引起。
Twenty-five adult mongrel dogs were used. An unilateral femoral vein was randomly ligated so that intraosseous hypertension ( IOH ) was produced in knee. Comprehensive indices of observation were used. The results showed that an animal model of IOH in the knee can be successfully produced ( including the inferior end of femur, the superior end of tibia, and the patella ) by ligating the femoral vein of one side. There was no statistically significant difference between cut and noncut group. It is obvious that the noncut's method is more simple and practicable. If DDO is not given after the model of IOH has been produced by using this method, the IOH can maintain for as long as half a year at least and can not restore to normal level by itself. But, after DDO, the pressure can drop down by 48.7 per cent immediately and the dropped pressure can maintain for as long as 4 months. The histological changes are roughly consistent with the degenerative osteoarthritis. Therefore, from clinical point of view, similar changes in human body may be induced by venous stasis of long duration due to various factors.
出处
《第一军医大学学报》
CSCD
1990年第1期56-59,共4页
Journal of First Military Medical University
关键词
骨内高压
钻孔减压术
降压作用
intraosseous pressure
intraosseous hypertension
decompression drilling operation
