摘要
过氧化物酶体增殖物激活受体-γ(PPAR-γ)是过氧化物酶体增殖物激活受体的一个亚类,参与脂肪形成、动脉粥样硬化、炎性反应、细胞周期调控以及肿瘤形成等过程,许多研究表明,PPAR-γ与甲状腺癌关系密切,它在甲状腺癌的发生、发展,以及临床诊断、预后判断中都扮演了重要的角色,有望成为甲状腺癌诊断和治疗的靶基因。
PPAR-γ is a subtype of peroxisome proliferator activated receptors. It participates in many of the pathophysiology processes, such as adipagenesis, artherosclemais, inflammatory reaction, cell cycle control, tumorigenesis and so on. Lots of studies suggest that PPAR-γ also palys an importment role in the thyroid carcinogenesis in its development,clinlcal diagnosis and prognosis judgement ,which makes it become a prom- ising target gene for the diognosis and therapy of thyroid cancer.
出处
《医学综述》
2006年第20期1240-1242,共3页
Medical Recapitulate
关键词
过氧化物酶体增殖物激活受体-Γ
甲状腺肿瘤
癌发生
诊断
治疗
预后
Peroxisome proliferator activated receptors gamma
Thyroid cancer
Carcinogenesis
Diognosis
Treatment
Prognosis
