摘要
大多数研究结果显示自身免疫性甲状腺疾病(AITD)与Th1/Th2型免疫反应有关。例如Graves病(GD)以Th2型细胞因子介导的体液免疫有关,乔本甲状腺炎(HT)以Th1型细胞因子介导的细胞免疫有关,而Graves眼病(GO)急性期以Th1型细胞因子介导的细胞免疫有关,慢性期以Th2型细胞因子介导的体液免疫有关。尽管也存在不同的结论,细胞因子网络和细胞因子平衡在自身免疫性疾病中确实发挥着重要作用。
Many studys showed that AITD is associated with Th1-or Th2-derived immune response. Such as GD is related to the humoral immunity mediated by Th2, HT is related to the cell immunity mediated by Thl, but GO is related to cell immune in its aute phase and humoral immune in its chronic phase. Although there are some different results, it is true that cytokines and its balance do play an important role in AITD.
出处
《医学综述》
2006年第19期1160-1163,共4页
Medical Recapitulate
