摘要
对经病理组织学确诊的２０例胃癌患者手术前行选择性动脉插管化疗，其中１２例手术，并与同期术前行全身静脉化疗的１０例胃癌患者比较。结果动脉插管化疗组除临床症状有不同程度的改善外，其胃癌原发灶和淋巴结转移灶中的癌细胞均有不同程度的变性坏死。两组比较有高度显著性差异（Ｐ＜０．０１）。作者认为，胃癌患者术前采用选择性动脉插管化疗，其近期抗癌效果好，毒副反应小，不仅可提高胃癌的手术切除率和根治率，对减少或防止术中癌细胞的医源性扩散、种植和术后复发也有重要的临床意义。
The effects of preoperative selective arterial perfusion chemotherapy(PSAPC) in the treatment of 20 cases of histologically confirmed gastric cancers is reported in which 12 patients were operated on,and a comparison with that of general chemotherapy in 10 cases of gastric cancers(as controls) was made.In the PSAPC group,besides the improvement of clinical symptoms and singns, the cancer off ifs of lesions in situ and metastatic lymph nodes have different degrees of degeneration and necrosis. This result show significant differences in two group comparison(p<0.01).We conclude that the PSAPC has good short-term effect and little side-effect. It can improve the resection rate and radical resection rate,and prevent the iatrogenic metastasis and implantation during operation,and decrease the postoperative recurrence of the patients with gastric cancer.
关键词
胃癌
手术前
动脉插管化疗
病理
Gastric cancer Preoperative arterial perfusion chemotherapy Clinico-pathological study
