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大面积脑梗死并高热老年患者的亚低温治疗疗效观察 被引量:3

Effect of Mild Hypothermia Therapy on Elderly Patients with Massive Hemispheric Infarction and Hyperpyrexia
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摘要 目的观察亚低温治疗对大面积脑梗死并高热老年患者生命体征的影响及其临床疗效。方法46例发病24h内入院的老年大面积脑梗死并高热患者随机分为亚低温组和对照组各23例。亚低温组给予33℃~35℃的低温治疗,对照组给予常规降温治疗,10d后评定两组患者的体温、心率等,并根据死亡率及神经功能缺损评分评估患者的预后。结果10d后,亚低温组患者的体温、心率均低于对照组,死亡率亦低于对照组,神经功能改善(P<0.05),预后较好。结论亚低温治疗老年大面积脑梗死并高热患者安全有效。 Objective To observe the effect of mild hypothermia on vital signs of the elderly patients with anterior circulation brain infarction (massive hemispheric infarction) and hyperpyrexia. Methods 46 elderly patients with massive hemispheric infarction and hyperpyrexia within the first 24 hours after onset were randomly divided into the control group and the hypothermia group with 23 cases in each group. The patients of the hypothermia group were treated with mild hypothermia therapy (33℃-35℃ ). Those of the control group were treated with routine hypothermal treatment. The temperature and heart rate of all patients were measured after 10 days; the prognosis was evaluated according to mortality and scores of Neurological Deficit Scale (NDS). Results For patients of the hypothermia group, the temperature and heart rate significantly reduced, death rate was significantly lower, the neurological func- lion distinctly improved and prognosis was better than the control group after 10 days treatment ( P "~0.05). Conclusion Mild hypothermia is safe and effective to elderly patients with massive hemispheric infarction and hyperpyrexia.
出处 《中国康复理论与实践》 CSCD 2006年第8期663-664,共2页 Chinese Journal of Rehabilitation Theory and Practice
关键词 脑梗死 高热 低温 预后 brain infarction hyperpyrexia hypothermia prognosis
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