摘要
Based on the generalized pulse spectrum technique that was previously developed for time-domain diffuse optical tomography, we propose a linear framework of time-domain fluorescence molecular tomography for simultaneous reconstruction of both the yield and lifetime of multi-fluorophores. The methodology is exemplified for mono-component case and validated with simulated data.
Based on the generalized pulse spectrum technique that was previously developed for time-domain diffuse optical tomography, we propose a linear framework of time-domain fluorescence molecular tomography for simultaneous reconstruction of both the yield and lifetime of multi-fluorophores. The methodology is exemplified for mono-component case and validated with simulated data.
基金
This work was supported by the National Natural Science Foundation of China (No. 60578008)National Basic Research Program of China (No. 2006CB705700).