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乳酸脱氢酶作为妊娠期高血压病生化监测指标的临床意义 被引量:6

Clinical Value of Lactic Dehydrogenase as a Biochemical Marker in Pregnancy-induced Hypertension Syndrome
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摘要 目的探讨乳酸脱氢酶(LDH)作为妊娠期高血压病生化监测指标的临床意义。方法回顾性分析我院2004年82例妊娠高血压综合征(简称妊高征)患者的临床资料(34例轻度子痫前期患者为Ⅱ组,48例重度子痫前期患者为Ⅲ组)。同时选取正常妊娠无并发症者80例作对照(Ⅰ组)。根据LDH水平(<600IU/L、600~800IU/L和>800IU/L)将妊高征患者分成A、B、C3组,分析3组患者的临床表现、并发症及围产结局。结果Ⅰ、Ⅱ、Ⅲ3组孕妇LDH水平间差别有显著性意义(P<0.01)。不同LDH水平患者临床表现、并发症及新生儿出生体重间差别有显著性意义(P<0.05)。结论乳酸脱氢酶能监测妊高征的病情进展,预测母婴预后。 Objective To evaluate the clinical value of lactic dehydrogenase (LDH) in pregnancy - induced hypertension syndrome. Methods 82 women with pregnancy - induced hypertension syndrome ( 34 with wild pre - eclampsia as Ⅱ group and 48 with severe preeclampsia as Ⅲ group) and 80 pregnant women ( Ⅰ group) without complication were studied prospectively in 2004. According to the level of LDH ( 〈600, 600 -800, 〉800 IU/L) , 82 patients were divided into A, B and C group, then analyse the clinical manifestation, complication and fetal outcome in A, B and C group. Results LDH levels were significantly different in Ⅰ , Ⅱ , Ⅲ group ( P 〈 0. 01 ). The clinical manifestation, complication and newborn' weight were significantly different in A, B, C group ( P 〈 0.01 ). Conclusion Lactic dehydrogenase can reflect the severity of pregnancy - induced hypertension syndrome and predict the prognosis of mother and newborn.
作者 刘奕 林明
出处 《中国全科医学》 CAS CSCD 2006年第20期1673-1674,共2页 Chinese General Practice
关键词 乳酸脱氢酶 高血压 妊娠性 妊娠并发症 Lactic dehydrogenase Hypertension, pregnancy - induced Pregnancy complications
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