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糖苷酶及其在糖基化合物改性中的研究 被引量:5

Progress in glycosidase and modification of glycoside
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摘要 利用糖苷酶对糖基化合物的糖基定向改造工程是目前一个研究的热点。通过对该领域最新研究成果调研,综述了糖苷酶的分类、催化机理及其在糖基化合物改性中的应用,其中着重阐述了β-D-葡萄糖醛酸苷酶在甘草酸生物改性中的应用。提出了糖苷酶的改造方法及其在糖基化合物改性中的研究策略。 Selectivity modification of glycoside by glycosidase is one of the most fascinating topics. From recent methodological advancements in this field, the classification, catalyzing mechanism and the application in the modification of glycoside by glycosidase were summarized in this review. Glycyrrhizin biotransformation by β- D-glucuronidase was focused. Some strategies on modification of glycoside were discussed here.
出处 《生物加工过程》 CAS CSCD 2006年第3期16-21,共6页 Chinese Journal of Bioprocess Engineering
基金 生物反应器工程国家重点实验室开放基金(F200-B-0209) 教育部工业生物技术重点实验室开放基金
关键词 糖苷酶 糖基化合物 改性 glycosidase glycoside modification
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