摘要
本实验以幼狗心脏为实验对象，应用冷冻蚀刻技术观察ＡＴＰ－ＭｇＣｌ２对缺氧－复氧幼狗心肌细胞，尤其是膜结构的影响。结果表明，缺氧－复氧对照组心肌细胞损伤较重，而ＡＴＰ－ＭｇＣｌ２组心肌细胞损伤轻ｑ提示，ＡＴＰ－ＭｇＣｌ２对缺氧－复氧幼狗心肌细胞质膜、线粒体等超微结构有保护作用。
The effect of energy-rich phosphate ATP-MgCl 2 on the lack oxygen-reoxygen myocardial cell especially on the membrane structure ,were observeed under transmissin electron microscope in baby dog heart by freeze repica technique. The results showde that lack oxygen-reoxygen injuries of baby dog myocardium in ATP-MgCl 2 group was slighter than the control group.This results revealed that the energy-rich phos-phate agent ATP-MgCl 2 had protective effects on plasma membrane and mitochondria of the myocardial cell in the ischemia-reperfused baby dog heart.
出处
《中国病理生理杂志》
CAS
CSCD
北大核心
1996年第5期456-458,共3页
Chinese Journal of Pathophysiology
基金
国家自然科学基金
关键词
冷冻蚀刻
缺氧
心肌细胞
Freeze etching · Anoxemia · Mitochondria
