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骨桥蛋白与肿瘤关系的研究进展 被引量:4

Research Advance of Osteopontin and It's Correlation with the Tumour
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摘要 骨桥蛋白是一种具有多种功能的磷酸化糖蛋白,其中含有特异的与细胞黏附及迁移有关的GRGDS序列。近年的大量研究证实,骨桥蛋白有助于许多肿瘤的生长、侵袭和转移,是一种新的肿瘤标记物,对大部分肿瘤来说,它是肿瘤治疗的一个潜在靶点。 Osteopontin is a multifunctional phosphoprotein containing GRGDS sequence which functions in cell adhesion and chemotaxis. Recently, osteopontin contributes to tumour development, invasion and metastasis. It is a novel marker of tumour and can be used as a potential therapeutic target for the majority of human tumors.
出处 《国际遗传学杂志》 CAS 2006年第3期235-238,共4页 International Journal of Genetics
基金 浙江省科技厅基金(No.2006C33060)
关键词 骨桥蛋白 肿瘤 生长 转移 治疗 Osteopontin Ttunour Development Metastasis Therapy
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参考文献26

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