摘要
RNA干涉(RNAi)是由双链RNA(dsRNA)引起的序列特异性基因沉默,这是目前研究的热点,具有广阔的应用前景.对RNAi的分子机制、生物功能、研究策略及RNAi技术在基因功能、基因治疗、植物品质改良等方面的应用进行了综述.
RNA interference(RNAi) is the sequence-specific gene silencing induced by double-stranded RNA(dsRNA). It becomes research hotspot at present. It has been applied in some aspects and will be used widely in the future. Molecular mechanisms, biological functions and research strategies of RNAi are reviewed. The applications of RNAi in gene function, gene therapy and plant quality betterment are also reviewed.
出处
《西北师范大学学报(自然科学版)》
CAS
2006年第5期105-111,共7页
Journal of Northwest Normal University(Natural Science)
关键词
RNA干涉
基因沉默
分子机制
RNA interference gene silencing molecular mechanism