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脑卒中后认知障碍的研究进展 被引量:27

Progress in poststroke cognitive impairment
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摘要 目的:综述脑卒中后认知障碍的研究进展,以便预防和治疗认知障碍,提高脑卒中后认知障碍患者的生活质量。资料来源:应用计算机检索万方数据库2000-01/2005-12与脑卒中后认知障碍相关的文章,检索词“认知障碍”,“痴呆”,“认知损害”,限定语种为中文;同时应用计算机检索Pubmed2000-1/2005-12期间的相关文章,检索词为“cognitiveimpairment”,“cognitivedisorder”,“dementia”,“rehabilitation”,并限定文章语言种类为“English”。资料选择:就检索到的140余篇文献进行筛选,选取与脑卒中后认知障碍有关的文章。资料提炼:共收集到相关文章24篇,将筛选到的文献分类,其中认知障碍评定的4篇,相关因素的9篇,药物治疗的6篇,康复治疗的5篇。资料综合:脑卒中后认知障碍的评定主要依靠简明智能状态检查表、功能综合评定量表、神经行为认知状态检查表等的检测;年龄、性别、疾病因素、药物因素、生物因素、日常生活活动能力等均是脑卒中后认知障碍的相关因素;脑卒中后认知障碍的药物治疗主要以他汀类、尼莫地平和一些中药为主;认知康复干预是脑卒中后认知障碍患者的常规治疗方法。结论:脑卒中后认知障碍对日常生活活动能力影响很大,应对其进行早期的预防和相应的治疗以提高患者的生存质量。 OBJECTIVE: To describe the development in research about cognitive impairment after stroke, so as to prevent and treat cognitive impairment and elevate the life quality of patients with cognitive impairment after stroke. DATA SOURCES: A computer-based search was conducted in Wanfang database for the Chinese articles about cognitive impairment after stroke published between January 2000 and December 2005 by using the key words of "cognitive impairment, dementia, cognitive handicap". Meanwhile, relevant English articles between January 2000 and December 2005 were searched in Pubmed with the key words of "cognitive impairment", "dementia" , "rehabilitation". STUDY SELECTION: 140 articles were selected firstly, and those related to the cognitive impairment after stroke were selected. DATA EXTRACTION: Totally 24 relevant articles were selected, which were classified, including 4 articles about evaluation, 9 articles about relevant factors, 6 articles about drug treatment and 5 articles about rehabilitation treatment. DATA SYNTHESIS" Cognitive impairment after stroke were mainly evaluated according to the mini-mental state examination (MMSE), functional comprehensive scale and neurobehavioral cognitive status examination (NCSE) etc. Age, sex, factors of disease and drug, biological factor, activity of daily living and so on were relevant factors of cognitive impairment after stroke. The drug treatment of cognitive impairment after stroke were mainly with statins, nimodipine and some Chinese medicines, and the intervention of cognitive rehabilitation were routine treatment of cognitive impairment after stroke. CONCLUSION: Cognitive impairment influences the activities of daily lift seriously. Therefore, early prevention and treatment facilitates to elevate the life quality of patients with cognitive impairment after stroke.
出处 《中国临床康复》 CSCD 北大核心 2006年第34期139-141,共3页 Chinese Journal of Clinical Rehabilitation
基金 国家"十五"攻关项目基金资助(2004BA703B09)~~
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