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^(99m)Tc-MIBI门控心肌断层显像在冠状动脉支架术后的临床价值 被引量:5

Clinical value of ~(99m)Tc-MIBI gated cardiac SPECT imaging in patients undergoing percutaneous transluminal coronary angioplasty plus stent implantation
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摘要 目的:探讨99mTc-甲氧基异丁基异腈(MIBI)门控心肌断层显像(G-MPI)在冠状动脉支架术后疗效评价、判断再狭窄以及预后评估的临床价值。方法:78例患者,冠状动脉支架术后3~12个月内均行G-MPI,其中31例有术前对照。33例复查冠状动脉造影(CAG)。随访13~24个月。结果:①31例复查G-MPI24例心肌灌注有改善,改善率为77.4%。②31例术后静息G-MPI所测左室射血分数(LVEF)较术前由(42.6±8.6)%上升至(49.7%±6.4)%,P<0.05;舒张末期容积(EDV)和收缩末期容积(ESV)分别由(158.2±55.3)ml、(92.6±44.9)ml明显下降到(133.9±39.9)ml、(71.2±28.7)ml,P均<0.01。③33例复查CAG患者,G-MPI对再狭窄诊断的敏感性、特异性、准确性为82.3%、85.0%、84.8%。④随访心脏事件发生率术后G-MPI灌注改善组(1.9%)与异常组(28.6%)之间有极显著差异(P<0.01)。结论:G-MPI对冠心病血运重建术后疗效评价、判断再狭窄以及预后评估具有重要的临床价值。 Objective:To assess the value of ^99mTc-methoxyisobutylisonitrile (MIBI) gated myocardial perfusion imaging (G-MPI) for evaluation of perfusion improvement, prediction of restenosis and cardiac event rate in patients undergoing successful stent implantation. Methods:Seventy-eight patients underwent G-MPI 3-12 months after operation. G-MPI was also performed in 31 patients before operation, and 33 patients underwent coronary angiography (CAG). The patieuts were followed up for 13-24 months. Results: ① Among 31 patients, perfusion imaging was improved in 24 cases, and the improved rate was 77.4%. ②LVEF was increased from(42.6 ± 8.6)% to (49.7% ± 6.4)%,P 〈 0.05; EDV and ESV were decreased significantly [(158.2 + 55.3) ml vs (133.9 ± 39.9) ml, and (92.6± 44.9) ml vs (71.2±28.7) ml, P 〈 0.01, respectively]. ③Restenosis was detected in 33 patients. Sensitivity,specificity and accuracy rates of G-MPI for predicting restenosis were 82.3%, 85.0%, 84.8%. ④During the follow-up, the incidence rate of cardiac events in non-ischemic group was significantly lower than that in abnormal group (1.9% vs 28.6%, χ^2 = 12.95,P 〈 0.01). Conclusion:G-MPI is an excellent tool to evaluate the effects of stent implantation and to predict restenosis, and cardiac events.
出处 《南京医科大学学报(自然科学版)》 CAS CSCD 北大核心 2006年第9期761-763,768,共4页 Journal of Nanjing Medical University(Natural Sciences)
基金 江苏省卫生厅2005年度医学科技发展基金资助(H200509)
关键词 冠状动脉疾病 经腔 经皮冠状动脉 血管成形术 门控心肌断层显像 coronary disease transluminal,percutaneous coronary angioplasty G-MPI
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参考文献11

  • 1李殿富,黄峻,冯建林,李建华,陈建伟,朱铁兵,王连生,杨志健,常国钧.门控心肌显像局部室壁运动异常对判断冠状动脉狭窄程度的价值[J].中华核医学杂志,2004,24(2):81-84. 被引量:24
  • 2李殿富,黄峻,张丽容.核素心肌灌注显像与冠状动脉造影结果的对比分析[J].南京医科大学学报(自然科学版),2003,23(1):38-40. 被引量:12
  • 3Berman DS,Abidov A,Kang X,et al.Prognostic validation of a 17-segment score derived from a 20-segment score for myocardial perfusion SPECT interpretation[J].J Nucl Cardiol,2004,11(4):414-423 被引量:1
  • 4Verheye S,Van Langenhove G,Sangiorgi GM.Pathophysiology of restenosis.In:Cardiac catheterization and percutaneous interventions[M].Hampshire UK:Taylor and Francis,2004:181-193 被引量:1
  • 5O'Rourke RA,Brundage BH,Froelicher VF,et al.American College of Cardiology/American Heart Association Expert Consensus document on electron -beam computed tomography for the diagnosis and prognosis of coronary artery disease[J].Circulation,2000,102 (1):126-140 被引量:1
  • 6冯建林,李殿富,李建华,徐兆强.门控心肌显像结合GS Quant软件评价左室功能[J].南京医科大学学报(自然科学版),2004,24(4):390-392. 被引量:7
  • 7Viek R,Michael SL.Nuclear imaging in patients with a history of coronary revascularization.In:Clinical Nuclear Cardiology[M].3rd ed.Philadelphea:Elsevier Mosby,2005:493-535 被引量:1
  • 8Deligonul U,Vandormael MG,Shah Y,et al.Prognostic value of early exercise stress testing after successful coronary angioplasty:importance of the degree of revascularization[J].Am Heart J,1989,117(3):509-514 被引量:1
  • 9Rosanio S,Tocchi M,Stouffer GA.Use of stress testing to evaluate patients with recurrent chest pain after percutaneous coronary revascularization[J].Am J Med Sci,1998,316 (1):46-52 被引量:1
  • 10Klocke FJ,Baird MG,Lorell BH,et al.ACC/AHA/ASNC guidelines for the clinical use of cardiac radionuclide imaging[J].Circulation,2003,108(11):1404-1418 被引量:1

二级参考文献17

  • 1Faber TL,Cook DC,Folks RD,et al.Left Ventricular function from gated SPECT perfusion images:an integated method[J].J Nucl Med,1999,40:650-659. 被引量:1
  • 2Masahiro T,Shinichiro K,Keiichi C,et al.Comparisonn of Emorv and Cedars-Sinai methods for assessment of left ventricular function from gated myocardial perfusion SPECT in patients with a small heart[J].Annals Nucl Med,2000,14:421-426. 被引量:1
  • 3Nichols K,Lefkowitz D,Faber T,et al.Echocardiographic validation of gated SPECT ventricular function measurements[J].J Nucl Med,2000,41:1308-1314. 被引量:1
  • 4Iskandrian AE,Verani MS.Nuclear Cardiac hmaging[M].3 th ed.New York:Oxford,2003.323-367. 被引量:1
  • 5Schiller NB,Shah PM,Crawford M,et al.Recommendations of the left ventricle by two-dimensional echocardiography.American Society of Echocardiography Committee on Standards,Subcommittee on Quantitation of Two-Dimensional Echocardiograms[J].J Am Soc Echocard 被引量:1
  • 6Kenneth Nichols,David Lefkowitz,Tracy Faber,et al.Echocardiographic validation of gated SPECT ventricular function measurements[J].J Nucl Med,2000,41:1308-1314. 被引量:1
  • 7Ednardo Cwajg,Jucylea Cwajg,Zuo-Xiang He,et al.Gated myocardial perfusion tomography for the assessment of left ventricular function and volumes:comparison with echocardiography[J].J Nucl Med,1999;40:1857-1865. 被引量:1
  • 8Iskandrian AE,Verani MS.Nuclear Cardiac Imaging[M].3 th ed.New York:Oxford,2003.121-136. 被引量:1
  • 9Berman DS, Hayes SW, Shaw LJ, et al. Recent advances in myocardial perfusion imaging [J]. Curr Prob in Card,2001,26:62 - 70. 被引量:1
  • 10Antman EM, Braunwald E. Acute Myocardial Infarction. In:Braunwald E, eds. Heart Diease[M] . 6thed. Philadelphea:Saunders, 2001. 1 185 - 1287. 被引量:1

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