摘要
目的研究^(99)Tc^m-甲氧基异丁基异腈(MIBI)门控心肌显像(G-MPI)判断冠状动脉(简称冠脉)支架术后再狭窄的价值。方法76例冠心病患者,支架术后3～12个月行负荷和静息G- MPI,随后2周内行冠脉造影(CAG),对上述结果进行分析。结果①在76例患者共107支行支架术的冠脉中,随访CAG示27例(35．5%)共32支(29．9%)冠脉出现再狭窄。②按经治疗冠脉数计算,G-MPI诊断再狭窄的灵敏度、特异性和准确性分别为84．4%、90．7%和88．8%,阳性预测值和阴性预测值分别为79．4%、93．2%。③G-MPI诊断再狭窄的灵敏度略好于非门控心肌显像(NG-MPI),但两者差异无显著性(84．4%与78．1%,X^2=0．41,P=0．522);G-MPI诊断再狭窄的特异性明显优于NG-MPI(90．7%与78．7%,X^2=4．16,P=0．041)。结论G-MPI诊断冠脉支架术后再狭窄准确、无创,具有重要的临床应用价值。
Objective To study the value of gated ^99Tc^m-methoxyisobutylisonitrile （MIBI） myocardial perfusion imaging （G-MPI） for restenosis after coronary stent implantation. Methods Stress and rest G-MPI were performed in 76 patients after （3 - 12 months） successful coronary stent implantation, also coronary artery angiography （CAG） was performed within two weeks. Results ①In all 76 patients of 107 vessels after coronary stent implantation, restenosis occurred in 27 （35.5%） patients of 32 （29.9%） vessel territories which was confirmed by CAG. ②The sensitivity, specificity and accuracy of G-MPI for detection of restenosis were 84.4% , 90.7% and 88.8% ; the positive and negative predictive value were 79.4% and 93.2%, respectively.③There was no difference of sensitivity between G-MPI and non-gated-MPI （ 84. 4% vs 78.1% ,χ^2 = 0.41, P = 0.522）, but the specificity of G-MPI was superior than non-gated-MPI （90.7% vs 78.7% ,χ^2 =4.16, P = 0.041 ）. Conclusion G-MPI seems to be an accurate, non-invasive method for detection of restenosis and has important clinical value.
出处
《中华核医学杂志》
CAS
CSCD
北大核心
2006年第6期363-365,共3页
Chinese Journal of Nuclear Medicine
基金
江苏省卫生厅2005年度医学科技发展基金(H200509)
