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显微激光薄化人胚胎透明带辅助孵出效果观察 被引量:1

Observation of laser zona pellucida thinning in assisted hatching
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摘要 目的:观察显微激光薄化人胚胎透明带进行辅助孵出的效果。方法:应用1.48μm二极管激光打孔仪对50个胚胎进行透明带薄化辅助孵出,另外51个胚胎作为对照,体外囊胚培养,观察囊胚形成及孵出情况。结果:薄化组囊胚形成率(50.0%)与对照组囊胚形成率(45.1%)间差异无统计学意义(P>0.05);但薄化组囊胚发动孵出率和囊胚完全孵出率(88.0%,59.1%)均高于对照组(34.8%,12.5%)(P均<0.05)。结论:显微激光薄化人胚胎透明带辅助孵出能提高囊胚孵出率,是优于传统辅助孵出技术的一个好方法。 Aim: To study the hatching efficacy of human embryos subjected to laser zona pellucida thinning. Methods:Zona pellucida thinning was performed on 50 embryos using a 1.48 μm diode laser, the rate of resulting blastocysts and the hatching and hatched blastocysts was compared with 51 control embryos. Results: There was no statistic significance in the rate of resulting blastocysts between the treated group (50.0%) and control group(45.1% ) (P 〉 0.05 ). The rates of hatching and hatched blastocysts were higher in the treated group ( 88.0% and 59. 1% ) than those in the control group (34.8% and 12.5% ) (P 〈 0.05 ). Conclusion: Laser thinning assisted hatching increases the rates of hatching and hatched blastocysts, thus has advantages over conventional assisted hatching techniques.
出处 《郑州大学学报(医学版)》 CAS 北大核心 2006年第5期889-891,共3页 Journal of Zhengzhou University(Medical Sciences)
关键词 辅助孵出 激光 体外受精-胚胎移植 胚胎透明带 assisted hatching laser in vitro fertilization-embryo transfer zona pellucida
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参考文献8

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