摘要
目的：分析Graves病（GD）甲亢在抗甲状腺药物（ATD）治疗后血清促甲状腺激素（TSH）值转归情况及其与治疗预后的关系，为寻找预后指标提供依据？方法：门诊就诊的GD甲亢患者86例，均选用ATD治疗，服药时间3～24个月，治疗及停药随诊期间定期复查TT3、TT4、FT3、FT4和TSH。结果：ATD治疗后TSH恢复正常的时间明显落后于甲状腺激素（TH）恢复正常的时间；治疗结束后第2年，TSH正常组复发率明显低于TSH减低组（x^2=5．2062，P=0．0225）。结论：ATD治疗过程中，TSH恢复正常的时间明显落后于TH降至正常的时间，血清TSH值可以作为判断ATD治疗预后的一个良好指标。
Objective： To observe the relationship of the TSH and prognosis of GD with ATD, and to find out the index related the prognosis. Methods： To treat 86 GD patients in clinic with ATD for 3 - 24 months, at the same time check the TF3, TF4, FT3, FT4 and TSH at intervals. Results： The time of recovery of TSH is later than TH obviously; the relapsing ration of TSH normal group is lower than the TSH decreasing group （ x^2 = 5.2062, P = 0.0225 ）. Conclusions： TSH can be regarded an index to judge the prognosis treated with ATD, The time of recovery of TSH is later than TH obviously.
出处
《华西医学》
CAS
2006年第3期450-451,共2页
West China Medical Journal
基金
深圳市科技局立项(JH200505300507A)
