摘要
目的通过应用藏药25味铜灰散治疗小鼠继发性棘球蚴病的疗效观察,探讨藏药治疗棘球蚴病的免疫机理及为临床更好的应用药物治疗棘球蚴病奠定一个良好基础。方法给予药物治疗90d后,解剖小鼠,检测各小鼠棘球蚴囊的湿重,对棘球蚴囊进行超微结构的观察。结果治疗90d后,棘球蚴囊病理及超微结构都有明显的变化。结论藏药25味铜灰散对小鼠棘球蚴有比较好的治疗作用,这将为棘球蚴病的临床治疗提供一个新的前景与思路。
The therapeutic effect of Tibetan medicine on the experimental secondary Echinococcus granulosus cysts（CE） was investigated, in which the ultrastructural observation on CE was carried out in mice undergone Tibetan medicine therapy 90 days after treatment, and the major judging indices included wet weight of CE, inhibition rate and histopathological changes in CE as demonstrated by light and electron microscopy. It was found that obvious damage on the cyst wall of hydatid could be observed under light microscopy on the 90 th day of treatment. Under electron microscopy, the laminated layer of cysts appeared to be not so homogenous, and the microvilli on the germinal layer became shorter and appeared to be unclear. In addition, pyknosis and karyorrhexis could be demonstrated in cells. It is evident that the Tibetan medicine shows certain therapeutic effect on E. granulosus cysts .
出处
《中国人兽共患病学报》
CAS
CSCD
北大核心
2006年第7期654-656,共3页
Chinese Journal of Zoonoses
关键词
棘球蚴病
藏药
超微结构
cysts of Echinococcus granulosus
Tibetan drugs
Albendazole
