摘要
包虫病是一种全球性人畜共患性寄生虫病,其治疗手段主要为手术治疗,但手术存在治疗不彻底、易二次感染等问题,因此药物辅助治疗也必不可少。阿苯达唑被认为是目前最有效的治疗药物之一,但其毒副作用大、血药浓度低、易产生耐药性。植物性药物有副作用少、价格低廉、与人体兼容性好等优点,寻找可有效治疗包虫病的草药或植物提取物,已成为防治研究的重要课题。本文概述了植物提取物和中药配方在体内外治疗包虫病的研究进展,以期为植物性药物在治疗包虫病方面提供参考。
Echinococcosis（hydatid disease）is a global zoonotic parasitic disease. At present,surgery remains the preferred treatment for this disease,but there are problems such as incomplete treatment and secondary infection. Therefore,adjuvant therapy of drugs is also essential. Albendazole is considered to be one of the most effective drug,but it has many side effects. In contrast,botanicals have fewer side effects,low cost,and high availability in the treatment of a wide range of diseases. Therefore,searching for herbs or plant extracts effectively treating echinococcosis has become an important topic. This paper summarizes the research progress in plant extracts and traditional Chinese materia medica in treatment of hydatid disease in vitro and in vivo,in order to provide reference for the treatment of echinococcosis by plant drugs.
作者
潘汝翀
张发斌
PAN Ru-chong;ZHANG Fa-bin(Medical College of Qinghai University,Xining 810008,China)
出处
《国际药学研究杂志》
CAS
CSCD
北大核心
2018年第4期258-262,共5页
Journal of International Pharmaceutical Research
基金
青海省科技厅资助项目(2014-ZJ716)
关键词
植物提取物
中草药
包虫病
plant extract
traditional Chinese materia medica
echinoeoceosis
