摘要
目的评价前列腺MRI三维(3D)立体重组在前列腺癌诊断和治疗中的作用。方法28例前列腺癌患者,年龄54～76岁,平均66．3岁。根据穿刺活检结果,14例为外周带癌,3例为中央腺体癌,另外11例患者为前列腺癌治疗后复查患者,其中9例采用内分泌治疗,2例采用放射性粒子置入治疗。所有患者均行直肠内线圈的轴面T2WI序列扫描,所得图像经3D-Doctor软件处理后得到3D重组立体图像。结果14例前列腺外周带癌患者的3D重组立体图像中,有4例显示癌区局限于外周带内,占位效应不明显,外周带形态未见变化;其余10例癌组织向外周带外生长,造成局部外周带增厚,包膜外凸。3例中央腺体癌患者3D图像表现为受累中央腺体体积增大,压迫相邻外周带。2例放射性粒子置入患者可以清楚地显示出放射性粒子在前列腺内的空间分布情况;9例内分泌治疗后患者可见前列腺整体和癌区的体积缩小,包膜外凸减轻。结论3D重组图像可以显示出前列腺外周带、中央腺体和癌区的立体位置关系,为穿刺活检提供了更直观的信息。前列腺MRI三维立体重组在前列腺癌诊断和治疗中可以发挥一定的辅助作用。
Objective To evaluate three-dimensional reconstruction of MRI images in diagnosis and therapy of prostate cancer. Methods Twenty-eight patients with proven prostate cancers were recruited in this study. Seventeen of them were diagnosed as having prostate cancer according to the ultrasound guided systemic biopsy. Their MR examinations showed fourteen lesions in the peripheral zone and three in the central gland of the prostate. The other eleven patients underwent MR examination after a period of treatment, including endocrinetherapy and brachytherapy. Using endorectal coil, a series of T2-weighted images were acquired on the axial plane. These source images were processed by 3D-Doctor software to reconstruct into three-dimensional images. Results In the fourteen patients with peripheral zone cancer, reconstruction images could display the 3D regions of cancer and the involvement of capsular. The outspread of central gland and the compression of peripheral zone in patients with central gland cancer could be revealed in the same way. The volumetric changes of the lesion and the prostate after endocrinetherapy could also be perceived through these 3D images. Similarly, radioactive seeds were revealed in a spatial manner that could be easily evaluated. Conclusion Three-dimensional reconstruction images were obtained in all patients. They were able to provide stereotyped information about the lesions and their surrounding tissues. MRI threedimensional reconstruction can be an adjunctive tool in the evaluation of prostate lesions.
出处
《中华放射学杂志》
CAS
CSCD
北大核心
2006年第7期695-698,共4页
Chinese Journal of Radiology
基金
首都医学发展科研基金资助项目(2002-3038)
关键词
前列腺肿瘤
磁共振成像
图像处理
计算机辅助
Prostate neoplasms
Magnetic resonance imaging
Image processing, computerassisted
