摘要
目的 研究快速成像序列动态增强对前列腺癌的检出和定性价值。方法 对经活检证实的 2 5例 ,临床证实的 6例 ,共 31例前列腺癌患者作了前瞻性增强MRI研究。先行SET1WI、快速自旋回波 (FSE)T2 W序列扫描 ,然后行快速多层面干扰梯度回波 (FMPSPGR)序列团注增强扫描 ,共 4个回合。研究病灶增强情况 ,并对增强后图像与常规FSET2 WI进行比较。结果 FMPSPGR增强后扫描 ,共发现病灶 2 9个 ,可疑病灶 1个 ;外周带 2 3例中增强早期很高信号 7例、高信号 8例、稍高信号5例、等信号 3例。中央带病灶 5例强化较弥漫 ,相对均匀。 31例中 5例仅由FMPSPGR增强扫描检出。动态增强对病灶的检出率与T2 WI均较高 ,可弥补常规序列检出的不足。结论 团注动态增强MRI对前列腺癌有较高的检出率 ,也有助于前列腺癌的定性 ,可作为提高检出率的补充手段。
Objective To evaluate the value of bolus dynamic enhancement MR imaging in the detection and diagnosis of prostatic carcinoma. Methods Thirty one patients with prostatic carcinoma were prospectively studied with bolus dynamic enhancement MR imaging. Their age ranged between 52 and 81 years (average 64 years). In 31 patients, 25 cases were confirmed by biopsy and 6 cases by clinic data. The spin echo T 1 weighted image, fast spin echo T 2 weighted image, and bolus dynamic enhanced FMPSPGR images were obtained in all cases. The immediate and consecutive 3 group scans (15-20 s for each) were performed and the 4th scan was repeated in 3-5 min following injection of 18-22ml Gd DTPA (Magnevist) within 10 second. Results The dynamic enhanced MRI identified 29 abnormal lesions and 1 suspicious lesion in 31 patients, but FSE T 2WI detected only 25 lesions. In early enhanced phase, the lesions presented as hyperintense signal with different degree in 20 cases, isointense signal in 3 cases, located in peripheral zone and the contrast between lesions and surrounding parenchyma turned down in delayed phase. Slight diffuse enhancement was seen in 5 lesions of central zone. Dynamic enhanced images had same or much higher detection rate,5 lesions were identified only in dynamic enhanced images. Conclusion Fast dynamic enhanced MRI has high detection rate and improves diagnosis in prostatic carcinoma. In addition, it is also useful for differentiation from other diseases.
出处
《中华放射学杂志》
CAS
CSCD
北大核心
2000年第6期392-396,共5页
Chinese Journal of Radiology
关键词
前列腺肿瘤
磁共振成像
造影剂
Prostatic carcinoma
Magnetic resonance imaging
Contrast media
