摘要
目的探讨乳腺微小钙化定位切除手术的应用及在乳腺癌早期诊断和治疗中的作用。方法对126例乳腺微小钙化患者行X线检查确定钙化灶位置,采用金属线定位和手术切除活检,确定钙化区乳腺的病理类型。结果126例临床触诊阴性乳腺微小钙化病例中,乳腺癌37例(27.2%),其中0期乳腺癌11例(29.7%),Ⅰ期乳腺癌20例(54.1%),Ⅱ期乳腺癌6例(16.2%)。对乳腺癌病例采用保乳手术、乳腺单纯切除术和改良根治术等治疗,术后中位随访时间为36个月,只有1例(2.7%)Ⅱ期乳腺癌患者出现远处转移,其余患者无瘤生存。结论乳腺微小钙化定位切除具有组织损伤小,可靠性高等特点,对提高乳腺癌的早期诊断率具有一定的临床应用价值。
Objective To evaluate the application of localized biopsy of microcalcification in breast and its role in the early diagnosis and treatment of breast cancer. Methods 126 patients with microcalcification in breast were detected by conventional X-ray mammography and were resected by wire localization technique. The pathological diagnosis of microcalcification in breast was determined. Results Of the 126 eases, 37 （27.2 % ） cases of breast cancer were diagnosed, including 11 （29.7 % ） patients with stage 0 breast cancer,20（54. 1% ） with stage Ⅰ , 6（16.2 % ） with stage Ⅱ. The surgical management was preservative operation,mammectomy and modified radical mastectomy et al. Only 1（2.7%） patient with stage Ⅱ disease developed a systemic relapse and other patients remained free of recurrent disease at a median follow-up of 36 months. Conclusion Localized biopsy of microcalcification in breast had low damaged and high reliability. The clinical application of the technique is promising in the early diagnosis and treatment of breast cancer.
出处
《实用癌症杂志》
2006年第2期165-166,172,共3页
The Practical Journal of Cancer
关键词
微小钙化
定位切除
乳腺癌
触诊阴性乳腺病灶
Microcalcification
Localized biopsy
Breast cancer
Nonpalpable breast lesions
