摘要
目的:评价帕珠沙星治疗泌尿生殖系统感染的临床疗效和安全性。方法:采用病例对照研究的方法将84例泌尿生殖系统感染患者随机分为两组,治疗组45例,给予帕珠沙星300 mg,ivd,q12h;对照组39例,给予左氧氟沙星200 mg,ivd,q12 h;疗程均为7-14 d。结果:治疗组和对照组的临床有效率分别为91.1%和89.7%(P>0.05),细菌清除率分别为92.2%和90.2%(P>0.05);不良反应发生率分别为8.9%和7.7%(P>0.05),两组间差别均无统计学意义。结论:帕珠沙星是治疗泌尿生殖系统感染安全有效的药物。
Objective: To evaluate the effect and safety of pazufloxacin in the treatment of genicourinary systems infection. Method: Eighty-four patients were divided into two groups (45 in trial group, 39 in control group ). The patients of trial group were given pazufloxacin 300mg, ivd, q l2h;The patients of control group were given levofloxacin 200mg,ivd,q12h;The course of treatment for both group were 7 d-14 d. Result: The effective rates of trial group and the control group were 91.1% and 90.2% respectively (P 〉 0.05)) ; bacterital clearance rate was 92.2% and 90.2% respectively ( P 〉 0.05) ; adverse reaction rate was 8.9% and 7.7% respectively(P 〉 0.05 ) ,there was no statistical difference between two groups. Conclusion: Pazufloxacin is an effective and safe antibacterial agent in treatment of genico urinary system infection.
出处
《中国药师》
CAS
2006年第7期656-657,共2页
China Pharmacist