摘要
目的比较角膜瓣的蒂部位于颞侧和上方的LASIK治疗近视对角膜知觉影响差异。方法随机性、前瞻性、单盲研究。本研究包含100例(200只眼)近视患者,所有病例的双眼屈光度相近、术前矫正视力≥1.0且可完全矫正。随机将患者一眼的角膜瓣蒂部置于上方,另一眼置于颞侧,然后进行常规LASIK手术。分别在术前、术后1天、1周、1、3、6个月和12个月时,使用Cochet-Bonnet角膜知觉计检查中央角膜知觉,对数据进行统计学分析。结果颞侧蒂组和上方蒂组的中央角膜知觉在LASIK术后各个时间点均比术前水平有不同程度的下降,颞侧蒂组角膜知觉在1个月时恢复到术前水平,上方蒂组则需要到术后3个月时才达到术前水平。颞侧蒂组和上方蒂组两组间的中央角膜知觉在LASIK术前没有显著差异；在术后1天、1周及1个月时差异有显著意义(P＜0.05)；在术后3、6个月和12个月时,两组间没有显著差异。结论颞侧蒂组与上方蒂组的中央角膜知觉在LASIK术后早期均显著下降,而颞侧蒂组的中央角膜知觉敏感度损失较小、恢复较早。
Objective To compare the differences in the effect of hinge Position on corneal sensation after LASIK. Methods This randomized prospective study comprised 100 patients （ 200 eyes） with similar myopia degree of two eyes. In one eye of a patient, a superior hinge was made and in the other eye, a temperal hinge was made randomly. Corneal sensation before surgery and 1 day, 1 week, and 1, 3,6 and 12 months after surgery were compared. Results The corneal sensation in eyes with both a temporal-hinge flap and a superior-hinge flap decreased during the postoperative period. The corneal sensation in eyes with a temporal-hinge almost recovered at 1 month after surgery, hut the corneal sensation in eyes with a superior-hinge flap at 3 months after surgery. Before surgery, here were no significant between-group differences in corneal sensation. At 1 day, 1 week, and 1 month after surgery, there were significant between-group differences in corneal sensation（ P 〈0.05）. At 3,6 and 12 months after surgery, there were no significant between-group differences in corneal sensation. Conclusions The loss of corneal sensation in eyes with a superior-hinge flap was greater than in eyes with a temporal-hinge flap, and recovery of corneal sensation in eyes with a temporal - hinge flap was earlier than in eyes with a superior-hinge flap.
出处
《临床眼科杂志》
2006年第3期199-201,共3页
Journal of Clinical Ophthalmology
