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肿瘤PET药物的现状和展望 被引量:14

Prospect and Status of PET Radiopharmaceuticals in Oncology
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摘要 随着正电子发射计算机断层显像技术(PET)的研发,PET药物在肿瘤科学研究及临床应用中具有越来越重要的作用。本文在肿瘤代谢显像、肿瘤细胞凋亡显像、反义显像、受体显像及基因表达监测等方面集中介绍肿瘤PET药物的进展情况及其发展前景。 With the research and development of the PET techniques, the PET radiopharma- ceuticals in oncology has played more and more important role in the tumor science study and clinical application. In this paper, the development of the tumor positron radiopharmaceuticals, including the tumor metabolic imaging, tumor cell apoptotic imaging, antisense imaging, receptor imaging and monitoring of gene expression is described.
作者 王荣福
出处 《核化学与放射化学》 EI CAS CSCD 北大核心 2006年第2期65-71,共7页 Journal of Nuclear and Radiochemistry
关键词 PET药物 正电子发射计算机断层显像 核医学 代谢显像 基因显像 肿瘤 PET radiopharmaceutical positron emission tomography nuclear medicine metabolic imaging gene imaging neoplasms
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参考文献31

  • 1Wahl R L.Principle and Practice of Positron Emission Tomography[M].Philadephia:Lippincott Williams & Wilkins,2003:157-251. 被引量:1
  • 2王荣福主编..符合线路探测正电子成像与临床[M].北京:北京大学医学出版社,2004:384.
  • 3王荣福.肿瘤:^(18)F-DG PET代谢显像[J].国外医学(放射医学核医学分册),1997,21(3):106-110. 被引量:13
  • 4Jager P L,Vaalburg W,Pruim J,et al.Radiolabeled Amino Acids:Basic Aspects and Clinical Application in Oncology[J].J Nucl Med,2001,42:432-445. 被引量:1
  • 5王荣福主编..核医学[M].北京:北京医科大学、中国协和医科大学联合出版社,2003:200.
  • 6Kelloff GJ,HoffmanJ M,JohnsonB,etal.Progress and Promise of FDG-PET Imaging for Cancer Patient Management and Oncologic Drug Development[J].Clin Cancer Res,2005,11 (8):2 785-2 808. 被引量:1
  • 7Matthies A,Hickeson M,Cuchiara A,et al.Dual Time Point ^18F-FDG PET for the Evaluation of Pulmonary Nodules[J].J Nucl Med,2002,43:871-875. 被引量:1
  • 8张建华,王荣福.符合探测正电子双时相显像临床应用的研究进展[J].北京医学,2005,27(7):433-438. 被引量:6
  • 9Conti P S.The Future of Radioimmunotherapy:a PET Perspective[J].Semin Oncol,2005,32(Suppl 1):63-67. 被引量:1
  • 10Souba W W,Pacitti A J.How Amino Acids Get Into Cells:Machnisms,Models,Menus and Mediators[J].J Parenter Enteral Nutr,1992,16:569-578. 被引量:1

二级参考文献99

  • 1张剑英,朱霖.^(99)Tc^m标记的乏氧组织显像剂[J].中华核医学杂志,2003,23(6):377-380. 被引量:8
  • 2Boerman O C, Oyen W J G, Corstens F H M. Between the scylla and charybdis of peptide radionuclide therapy:hitting the tumor and saving the kidney[J]. Eur J Nucl Med, 2001, 28:1447-1449. 被引量:1
  • 3Forssell-Aronsson E, Bernhardt P, Nilsson O, et al. Biodistribution data from 100 patients iv. injected with 111In-DTPA-D-pheloctreotide [J]. Acta Oncol, 2004, 43(5): 436-442. 被引量:1
  • 4Bushnell D, Menda Y, O' Dorisio T, et al. Effect of intravenous amino acid administration with Y-90 DOTA-Phe1-Tyr3-octreotide (SMT487[Octreo TherTM])treatment[J]. Cancer Biother Radiopharm,2004, 19(1): 35-41. 被引量:1
  • 5Pauwels S, Barone R, Walrand S, et al. Practical dosimetry of peptide receptor radionuclide therapy with 90Y-labeled somatostatin analogs[J]. J Nucl Med, 2005, 46(1 suppl): 92S-98S. 被引量:1
  • 6Moll S, Nickeleit V, Mueller-Brand J, et al. A new cause of renal thrombotic microangiopathy: Yttrium-90-DOTATOC internal radiotherapy[J]. Am J kidney Dis, 2001,37(4): 847-851. 被引量:1
  • 7Bodei L, Cremonesi M, Zoboli S, et al. Receptor-mediated radionuclide therapy with 90Y-DOTATOC in association with amino acid infusion, a phase Ⅰ study[J]. Eur J Nucl Med Mol Imaging, 2003,30(2): 207-216. 被引量:1
  • 8Rolleman E J, Valkema R, de Jong M, et al. Safe and effective inhibition of renal uptake of radiolabelled octreotidc by a combination of lysine and arginine[J]. Eur J Nucl Med Mol Imaging, 2003, 30(1):9-15. 被引量:1
  • 9Barone R, Pauwels S, De Camps J, et al. Metabolic effects of amino acid solutions infused for renal protection during therapy with radiolabelled somatostatin analogs[J]. Nephrol Dial Transplant, 2004, 19(9): 2275-2281. 被引量:1
  • 10Barone R, Borson-Chazot F, Valkema R, et al. Patient-specific dosimetry in predicting renal toxicity with 90Y-DOTATOC: relevence of kidney volume and dose rate in finding a dose-effect relationship [J]. J Nucl Med, 2005, 46(lsuppl): 99s-106s. 被引量:1

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