摘要
为筛选大叶紫薇叶中具有降血糖活性的成分,采用3T3-L1细胞葡萄糖消耗模型作为检测手段,对大叶紫薇叶提取物采用HP-20树脂吸附、溶剂萃取、制备薄层分离和制备高效液相分离,导向筛选具有降血糖作用的各分离组分。结果发现,大叶紫薇叶中corosolic acid、熊果酸和总三萜具有降血糖活性。
To screen of Lagerstroemia specious leaves constituents with hypoglycemic activity, 3T3-L1 adipocytes were stimulated by seperation component to measure the effect of glucose consumption activity. The components in Lagerstroemia specious leaves extract were separated by HP-20 resin, solvent extraction, PTLC and PHPLC. The result showed that the components of corosolic acid, ursolic acid and total triterpenes have the effect of hypoglycemic activity.
出处
《食品与生物技术学报》
CAS
CSCD
北大核心
2006年第3期67-71,共5页
Journal of Food Science and Biotechnology
基金
河南省科技攻关项目(324010016)
关键词
大叶紫薇
3T3-L1细胞
降血糖
结构
Lagerstroemia specious leaves
3T3-L1 adipocytes
hypoglycemic activity
structure
