摘要
目的报道应用显微外科治疗难治性癫痫的临床效果。方法应用三维痫灶定位诊疗计划对163例顽固性癫痫患者进行术前、术中致痫灶三维精确定位,然后在显微镜下采用几种术式结合的方法手术处理致痫灶、致痫网。术后随访1～2年,回顾性分析显微外科手术治疗的临床效果。结果结果发现术后癫痫发作完全消失52例(31．90%),发作显著改善83例(50．92%),改善较好10例(6．13%),改善较差15例(9．20%),发作无改善3例(1．84%),手术总有效率为88．96%,无效率为11．04%,术后88．96%以上的患者生活质量均有一定程度的提高。结论应用显微外科技术切除癫痫病灶可以明显减少术后并发症,提高临床疗效。
Objective To explore the therapeutic effect of patients with intractable by microsurgical operation. Methods All patients assisted by a 3-dimensional precise localization system of epileptic foci for epilepsy diagnosis and the epileptogenic focus and comprehensive surgical measures were taken for the treatment of isolated epileptic foci and their network. The outcomes of 50 patients in the following up 1-2 years were defined. A retrospective review was conducted. Results In this group, Excellent 53 cases （ 31.90% ） ; good 83 cases （ 50. 93 % ） ; moderate 10 cases （ 6. 13 % ） and poor 18 cases （ 11.04 % ）. The effective rate was 80%. Conclusion The microsurgical management is an effective approach for treatment of refractory epilepsy.
出处
《中华显微外科杂志》
CSCD
北大核心
2006年第3期192-193,共2页
Chinese Journal of Microsurgery
关键词
癫痫
显微外科手术
Intractable epilepsy
Microsurgical operation
