摘要
对105例癫痫患者在发作间期进行了单光子发射计算机断层扫描(SPECT)检查,并对其中20例在发作期也进行了扫描。该20例中,发作期局部脑血流均较发作间期有不同程度提高,将两组图像经减影处理后得出一组减影图像,该减影图像可显示出血流改变区即致痫灶的具体大小及形态,以此结果指导手术。10例发作完全控制;6例发作减少75%以上;3例减少50%;1例无改善,总有效率达95%。术后半年对其中5例进行了SPECT复查,并与术前发作间期进行减影处理,发现除皮质切除部位外,脑血流灌注均有不同程度改善。
SinceApril1991,105patientswithepilepsywereexaminedwithSPECTimagingduringinterictalperiod.IctalSPECTimagingwasalsoexaminedin20casesamongthemandrevealedthattheregionalcerebralbloodflowwasincreasedbycomparingwiththatininterictalphase.Aftersubtractprocessing,thesizeandshapeofepilepticfociweredisplayedclearly.Operationswereperformedac-cordingtothesefindings.Seizureswerecompletelycontroledintencases,decreasedbymorethan75%insix,morethan50%inthre,andunchangedinone.Thetotalefectiveratereachedto95%.Halfayearafteroperation,SPECTimagingwasdoneinfivecasesandsubtractprocesingwasmadetothatofpreoperativeinterictalphase.Theresultsshowedthatthebrainbloodflowelevatedinsomedegreeex-ceptthesiteofresectedcotex.
出处
《中华神经外科杂志》
CSCD
北大核心
1996年第5期295-298,共4页
Chinese Journal of Neurosurgery
关键词
癫痫
手术
CT
痫灶定位
EpilepsySurgerySPECTEpilepticfocilocatization