摘要
目的:总结分析21例恶性黑色素瘤病例的临床资料,探讨合理有效的治疗方法。方法:对21例恶性黑色素瘤病例的临床表现、治疗方法及预后进行回顾性研究。结果:21例中男女之比为1.1∶1,平均发病年龄为41.7岁,上、下颌之比为2.5∶1,颈淋巴结转移率为52.9%,3年、5年存活率分别为28.6%、23.8%。结论:口腔粘膜恶性黑色素瘤预后很差,包括手术、冷冻、免疫治疗等的综合治疗应是目前提倡的治疗方法。
Objective： To explore effective methods for the treatment of oral mucosa melanomas by reviewing 21 cases of patients. Methods. A retrospective research of 21 cases of oral mucosa melanomas was done, and the clinical symptom, therapeutic methods and prognostic factors were recorded and estimated. Results： Of the 21cases, the ratio of males to females was 1.1 ： 1, the average age was 41.7 years, the ratio of maxilla to mandible was 2.5.1, metastasis rate of cervical lymphnode was 52.9%, and survival rate of 3 and 5 years was 28, 6% and 23.8% respectively. Conclusion： The prognosis of melanoma was very poor, and combining therapies of operation, cryosurgery and immunotherapy should be advocated.
出处
《武汉大学学报（医学版）》
CAS
2006年第3期330-331,370,共3页
Medical Journal of Wuhan University
