摘要
用DNA重组技术得到的含甲肝病毒基因的重组痘苗病毒,可在家兔体内产生ELISA竞争抑制与中和抗体。基础免疫后,动物体内竞争抑制抗体滴度为10,加强免疫后达到80。由重组病毒产生的抗体中和指数比甲肝病毒产生者略低。
Recombinant vaccinia virus containing hepatitis A virus gene could induce ELISA competition inhibition and neutralizing antibodies in rabbits. After primary immunization, the ELISA antibody titer was about 1 : 10. But after boost, the antibody titer rose to 1 :80. The neutralizing index of the antibody induced by recombinant viccinia virus was slightly lower than that induced by HAAg.
出处
《病毒学报》
CAS
CSCD
北大核心
1990年第3期216-218,共3页
Chinese Journal of Virology
关键词
甲型肝炎病毒
重组痘苗病毒
抗体
Hepatitis A virus Vaccinia virus Neutralizing antibody
