摘要
目的：观察蔓托洛尔对慢性心力衰竭惠者的疗效。方法：随机选择慢性心力衰竭患者60例，其中关托洛尔治疗组34例（6．25-25mg／次，bid或tid）和对照组26例。治疗6个月，观察美托洛尔对患者症状、心功能的影响。结果：治疗组较对照组左心宣射血分数升高（5004±2％VS43％±1％，P〈0．01），左心室收缩未期客积下降（133±58VS141．2±55，P〈0．01）；治疗组治疗前、后比较，左心宣舒张期容积下降（P〈0．05）。结论：常规治疗基础上，应用美托洛尔能显著改善慢性心力衰竭患者的症状压心功能。
Objective： To observe the therapeutic effect of metoprolol in patients with chronic heart failure （CHF）. Methods： Sixty patients with CHF were selected randomly. The patients were divided into metoprolol group （34 cases,6. 25-25 nag, bid or tid） and control group （26 cases）. The efficacy of metoprolol on patient＇s symptoms and heart function were observed 6 months after treatment. Results, Left ventricular ejection was increased （50%± 2% vs 43% ±1%, P〈0. 01） and left ventricular systolic volume was decreased （1 33.0 ± 58 vs 141.2 ± 55, P〈0. 01） in metoprolol group than those in the control group. Left ventricular end-diastolic volume decreased in metoprolol group compared with that of at haseline（P〈0.05）. Conclusion： On the basis of routine therapy, metoprolol can improve the symptoms and heart function significantly in patients with CHF.
出处
《内科急危重症杂志》
2006年第2期67-68,75,共3页
Journal of Critical Care In Internal Medicine
关键词
心力衰竭
美托洛尔
治疗
Heart failure Metoprolol Treatment
