摘要
目的：比较两种方法治疗恶性胸腔积液的疗效。方法：随机将69例恶性胸腔积液患者分为治疗组（A组，n=36）和对照组（B组，n=33）。A组采用一次性中心静脉导管行胸腔穿刺并置入胸腔，持续引流胸水后再注入顺铂，置管时间平均20d；B组采用传统方法胸腔穿刺放胸水，每周1次穿刺放液后注入顺铂，80-100mg／次，每周1次，连续3周，1个月后观察两组的疗效及不良反应。结果：A组有效率为88．9％，B组有效率为54．5％，两组疗效差异有显著性（P〈0．05），两组不良反应及并发症的发生率无显著性差异（P〉0．05）。结论：中心静脉导管胸腔内置入持续引流胸水后再注入顺铂治疗恶性胸腔积液安全有效，操作简便。
Objective： To compare the efficacy of two different ways on malignant plural effusion. Methods： Malignant plural effusion was treated by plural puncture and continuous drainage with central venous duct following injection of cisplatin （group A, n = 36） ; and was treated by routine way of plural puncture weekly, following injection of cisplatin for 3 weeks （group B, n = 33）. The curative effect and side effect were recorded and compared between the two groups 1 month later. Results： The response rate in group A and B as 88.9 % and 54.5 % respectively （ P 〈 0.05）, whereas there was no marked difference in side effects between the two groups （ P 〉 0.05）. Conclusion： It＇s safe, effective and convenient to treat malignant plural effusion with continuous drainage by central venous duct and administration of cisplatin.
出处
《山东大学学报（医学版）》
CAS
北大核心
2006年第4期426-428,共3页
Journal of Shandong University:Health Sciences
关键词
导管插入术
中心静脉
穿刺抽液术
胸腔积液
恶性
Catheterization, central venous
Paracentesis
Pleural effusion, malignant
