摘要
目的:观察中药配合化疗治疗晚期鼻咽癌的临床疗效。方法:将62例晚期鼻咽癌患者随机分为中化组(中药加化疗)和单化组(单纯化疗),对两组治疗前后肿瘤病灶、1年生存率、1年无进展生存率、机体体能状态计分、T细胞亚群、自然杀伤细胞活性及化疗后毒副反应等指标进行临床疗效分析和组间比较。结果:中药配合化疗治疗晚期鼻咽癌1年无进展生存率为62.50%,较单纯化疗组(23.33%)显著提高(P〈0.05),可降低化疗导致的Ⅲ-Ⅳ度WBC减少及恶心呕吐、食欲下降发生率,改善化疗期间患者的体能状况,提高机体细胞免疫功能。结论:中医辨证治疗在延缓肿瘤进展、提高化疗耐受性以及维护机体免疫功能方面有明显优势.申西医结合的综合治疗是晚期鼻咽癌曼适宜的选择。
Objective: To observe the clinical effects on nasopharyngeal cancer treated by traditional Chinese medicine and chemotherapy. Method: 62 cases were randomly divided into traditional Chinese medicine group and chemotherapy. The neoplastic focus before and after treatment , survival rate of one year , non - advanced survival rate of one year, tallies of physical ability, T cell subpopulation and side effects after chemotherapy were analysed and compared between the two groups. Results: non - advanced survival rate of one year in traditional Chinese medicine group and chemotherapy group was 62.50% ,which higher than that in chemotherapy group (23.33 % ) ( P 〈 0.05 ). The combined therapy could decrease the incidence of Ⅲ - Ⅳ degree leukopenia , nausea, vomiting and anorexia caused by chemotherapy, impro~,e patient, s physical ability and increase cellular immune function. Conclusion: The therapy of combination of Chinese traditional and western medicine was an effective treatment for late nasopharyngeal cancer.
出处
《湖南中医杂志》
2006年第2期1-2,56,共3页
Hunan Journal of Traditional Chinese Medicine
关键词
鼻咽肿瘤/中西医结合疗法
Nasopharyngeal neoplasms/integrated Chinese traditional and western medicine therapy